Halazepam is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Halazepam is used to relieve anxiety, nervousness, and tension associated with anxiety disorders.

Halazepam (Paxipam) is no longer commercially available in the United States.

Common adverse effects are: hypotension, nausea, xerostomia, confusion, headache. Alcohol should be avoided while taking Paxipam as it causes drowsiness as well. Medications that also cause drowsiness should not be taken along with Paxipam. These include: Antidepressants, Pain relievers, Seizure medications, Muscle relaxants, Antihistamines, Sleeping pills and sedatives.

Excerpt from NCATS:
https://drugs.ncats.io/substance/320YC168LF

Halazepam

Duration: A less common prescription benzodiazepine and derivative of Nordazepam. Also known as Paxipam, it is no longer prescribed in the USA. Sedating, hypnotic and anxiolytic. High doses may induce amnesia and lowered inhibitions.
Route	Onset	Duration	After Effects
Tripsit Factsheets
Excerpt from Tripsit Factsheets: http://drugs.tripsit.me/halazepam
All ROAs:	15-45 minutes	8-14 hours	12-40 hours
Avoid: All other CNS depressants.
Effects: Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.

Halazepam is not commercially available in the United States.

What should I avoid while taking Halazepam?

Halazepam is habit forming. You can become physically and psychologically dependent on the medication.

Use caution when driving, operating machinery, or performing other hazardous activities. Halazepam will cause drowsiness and may cause dizziness. If you experience drowsiness or dizziness, avoid these activities.

Avoid alcohol while taking halazepam. Alcohol may increase drowsiness and dizziness caused by halazepam.

Halazepam may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.

Interactions:

Drug Interactions (341) Alcohol/Food Interactions (1)

What other drugs will affect Halazepam?
Halazepam may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.

Antacids may decrease the effects of halazepam. Separate doses of an antacid and halazepam by several hours whenever possible.

Drugs other than those listed here may also interact with halazepam. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

A total of 341 drugs are known to interact with Halazepam.

• 26 major drug interactions
• 282 moderate drug interactions
• 33 minor drug interactions

Halazepam Drug Information:
https://www.drugs.com/mtm/halazepam.html

While its structure may be similar to chlordiazepoxide and diazepam, it has both less toxicity and less tendency to cause paradoxical hostility and aggression than either of them. This compound belongs to the class of organic compounds known as 1,4-benzodiazepines.

Metabocard for Halazepam:
http://www.hmdb.ca/metabolites/HMDB0014939

Halazepam Monograph:
http://www.inchem.org/documents/pims/pharm/pim160.htm

Halazepam Safety Data Sheet (PDF 5 pages):
https://www.caymanchem.com/msdss/18290m.pdf

Halazepam:

Halazepam was marketed as an anti-anxiety agent in 1981. However, Halazepam is not commercially available in the United States because it was withdrawn by its manufacturer for poor sales.

• A benzodiazepine derivative
• It was used for the treatment of anxiety
• Adverse effects include drowsiness, confusion, dizziness, and sedation.