Methyldienolone is an anabolic steroid that was researched in the early 1960's, but never sold as a prescription drug. It is a nandrolone-based compound, modified to be orally active and to have greatly increased anabolic properties. Methyldienolone is a close chemical cousin of methyltrienolone, one of the strongest steroids profiled in this reference. Methyldienolone is not quite as potent, however it remains quite strong next to most commercial agents. Animal tests find it to be 5 times more potent than Dianabol, 10 times more potent than methyltestosterone, and 13 times more potent than Primobolan on a milligram for milligram basis. Although the real world relevance of these values may be questionable, methyldienolone is well favored by bodybuilders for its ability to promote lean muscle gains with minimal side effects.

Methyl-D Side Effects (Estrogenic):
Methyldienolone is not aromatized by the body, and is not measurablyestrogenic. lt is of note, however, that based on its structure methyldienolone likely displays significant binding affinity for the progesterone receptor. The side effects associated with progesterone can be similar to those of estrogen, including negative feedback inhibition of testosterone production and enhanced rate of fat storage. Progestins also augment the stimulatory effect of estrogens on mammary tissue growth.

Methyl-D Side Effects (Androgenic):
Although classified as an anabolic steroid,androgenic side effects are still common with this substance.

Methyl-D Side Effects (Hepatotoxicity):
Prolonged or high exposure may result in liver damage. In rare instances life-threatening dysfunction may develop. It is advisable to visit a physician periodically during each cycle to monitor liver function and overall health. Intake of cl 7-alpha alkylated steroids is commonly limited to 6-8 weeks, in an effort to avoid escalating liver strain.

Methyl-D Side Effects (Cardiovascular):
Although not studied in humans, the high relative potency, oral route, and non-aromatizable nature of methydienolone suggests that this agent is extremely prone to negatively altering lipid values and increasing atherogenic risk.

Methyl-D Side Effects (Testosterone Suppression):
All anabolic/androgenic steroids when taken in doses sufficient to promote muscle gain are expected to suppress endogenous testosterone production. Without the intervention of testosterone-stimulating substances, testosterone levels should return to normal within 1-4 months of drug secession. Note that prolonged hypogonadotrophic hypogonadism can develop secondary to steroid abuse, necessitating medical intervention.

Methyldienolone Thread 2004:
Without a doubt, Methyldienolone is the most potent prosteroid ever developed and sold in the world to date as it is about 1.1X as anabolic as Methyl-1-Testosterone is while being only 15% as androgenic.

Methyldienolone Updates:
Last month, I discussed an amazing new prosteroid called Methyldienolone (17a-methyl-17b-hydroxyestra-4,9(10)-3-one), which is the most potent prosteroid ever developed. I've been conducting a little experiment with this stuff and three guys - well, two guys and a gal (n = 3). I realize the more science-minded and statistically savvy of you will realize this study is not powerful enough to really prove (excuse me; "show a high degree of correlation to") anything. But the raw data speaks for itself. Let's take a look at the progress our test subjects have made.

a synthetic, orally active anabolic-androgenic steroid (AAS). Methyldienolone is on the World Anti-Doping Agency's list of prohibited substances