Oxymestereone is anabolic-androgenic steroid, a methylated derivative of testosterone. The drug was developed in 1960 and was in clinical use under brand names Oranabol, Anamidol, Balnimax, Sanabol, and Theranabol, however, it was discontinued later.

Oxymestereone:
https://drugs.ncats.io/drug/4R73K9MRMX

Oxymesterone is an anabolic steroid abused by some athletes and is tested for in regular preventive doping control analysis. Oxymesterone and other steroids can be detected in human urine using liquid chromatography/electrospray ionization orthogonal acceleration time-of-flight mass spectrometry (LCoaTOFMS) and gas chromatography/electron ionization orthogonal acceleration time-of-flight mass spectrometry (GCoaTOFMS), using methods that have been developed in order to acquire accurate full scan MS data to be used to detect designer steroids.

Belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans.

Metabocard for Oxymesterone:
https://hmdb.ca/metabolites/HMDB0006027

Oxymesterone is a potent oral anabolic steroid derived from testosterone. In structure, it is most closely related to 4-hydroxytestosterone, differing only by the addition of a c-17 alpha methyl group, which makes oral dosing viable. Like its non-methylated analog, oxymesterone remains an effective lean-tissue-building steroid with only a minimal to moderate androgenic component. It has no known estrogenic or progestational activity, and no discernable ability to cause side effects related to female sex hormones. Oxymesterone is a "clean" drug among oral steroids: potent, non-aromatizable, and primarily anabolic in nature. According to the standard laboratory assays, oxymesterone is over three times more anabolic than methyltestosterone, with only half the androgenicity. Closer comparisons to methyltestosterone, which may seem structurally logical, do not hold up well in practice, given the sharp contrasts in relative effects between these drugs. The differences are as drastic as their applications, with methyltestosterone being used almost exclusively for bulking phases of training while oxymesterone would fit most comfortably with cutting cycles or competitive athletics.

Oranabol History:
Oxymesterone was first closely described in 1956. It was developed into a medicine during the early 1960's by Societa Farmaceutici (Italy), which filed for patent protection on this compound in at least three countries including the United Kingdom, the United States, and Italy. This drug saw limited clinical use as a prescription agent under the Oranabol brand name in Spain and Italy, and under the names Anamidol, Balnimax, Sanabol, and Theranabol in other countries including Japan, the UK, and the Netherlands. Oxymesterone ultimately enjoyed little commercial success, and has been unavailable as a prescription drug worldwide for more than three decades now. It was never released in the United States. At very best, only a small handful of U.S. athletes have experimented with this obscure anabolic steroid over the years, and certainly very few in recent times. By the 1990's, oxymesterone had already become a forgotten relic of early steroid development. In all this time there has been limited mention of its use in the medical literature.

Oranabol - oxymesterone:
https://steroid.to/oranabol-oxymesterone

Similar to Winstrol:
A moderately potent, lean mass developing anabolic steroid that favors competition athletes. Although structurally very similar to methyltestosterone, this non-estrogenic compounds actions and effects are far more akin to the DHT-derivative Winstrol, and therefore ideal for latter cutting cycle inclusion. Like Winstrol, Oranabol is perfect for athletes and bodybuilders who crave strong, lean, well-defined physiques.

The recommended dosage for Oranabol users is 20-40 mg/day for 6-8 weeks, which is often enough to keep blood serum levels well above baseline with this particular drug. Its anabolic and androgenic effects are typically dose dependent and extremely supportive of testosterone-based cycles. Again, similar to both Winstrol and Anavar, Oranabols very low androgenicity makes it safe for female usage. Its recommended dosage and duration for women is 10 mg/day for no more than 4 weeks.

Oranabol:
https://www.steroid.com/Oranabol.php

Mild Oral Compound:
Since it is an oral steroid, oranabol includes a c-17 alpha methyl group that allows it to not get destroyed by the liver. On paper, it is about 3 times more anabolic than testosterone, and about half as androgenic. Hence, it can be considered as a mild oral compound, at least compared to other steroids. Oranabol does not aromatize, which means that there is no risk of estrogen increase in the body. Since it is mostly anabolic, and doesn't aromatize, it was popularly used as part of a cutting cycle or as a finisher, to harden muscles without water retention.

History:
Interestingly, oxymesterone never got enough popularity in the bodybuilding community. As a result, it has not been available for many years, and most probably, there are two major reasons for that. First of all, it was a bit too androgenic for females to use. Secondly, due to competition from other orals, such as winstrol and proviron, oranabol had few chances of becoming popular among men. As a result, there isn't enough evidence that you could find it in today's black market.

In fact, the last time it was spotted was around the late 1990s.

Half life:
The half life of oxymesterone is about 8 hours, which is typical of an oral anabolic steroid. However, it is important to remember that half life is NOT the active life in the system. Usually, a compound is active in the body for about 3-4 times as long as the half life is. Half life simply means that half the compound will be available in that amount of time, and the other half will get depleted. In this particular case, after 8 hours only half of the oxymesterone will be left in the body.

it is not known how long the detectable time was with oranabol, but based on its peers, we can assume it was around 2-3 weeks.

Oranabol (oxymesterone):
https://www.evolutionary.org/oranabol-oxymesterone/

2015 Article:
A paper recently published in Drug Testing and Analysis outlines how scientists from the National Anti-Doping Laboratory in Beijing (China) identified previously unknown metabolites of oxymesterone. This could increase the chances of detection in athletes who use this performance-enhancing drug. Oxymesterone is a commonly abused anabolic androgenic steroid that has been banned by the World Anti-Doping Agency (WADA). The team used human cell cultures and urine samples from two adult males to study the biotransformation of the compound. Following analysis by GC-MS/MS, the total ion chromatographs of the blank and the positive samples were compared, leading to the identification of seven new metabolites.

Although this particular steroid is tested for during doping analysis, laboratories are currently unable to detect it in urine after 2 days. The structures of the seven previously unknown metabolites are yet to be confirmed, however, two have been tentatively assigned. According to the researchers, these two metabolites could facilitate oxymesterone detection in the future, by extending the detection window to 4 days.

Seven new metabolites of anabolic steroid identified:
https://www.bioanalysis-zone.com/seven-new-metabolites-of-anabolic-steroid-identified/

Another 2015 Article:
Scientists at the National Anti-Doping Laboratory in Beijing have just published details of experiments on the commonly abused anabolic steroid oxymesterone, which should make its detection easier in the future. Writing in Drug Testing and Analysis, they explained how they found seven new metabolites of the drug, following a GC/MS analysis of a human hepatocytes cell line and human urine. The structures of two of the metabolites were assigned tentatively and will have to be confirmed by synthesis. Once they are confirmed and integrated into drug testing programs they will extend the testing window for oxymesterone.

Currently, the parent drug is normally targeted during doping analysis but it cannot be seen in urine after 2 days. The two metabolites will double the detection window to 4 days, providing more ammunition to the testing labs.

New metabolites found for common anabolic steroid:
https://analyticalscience.wiley.com/do/10.1002/sepspec.14ec0834db3/full/

Oxymesterone Pharmaceutical Chemical Safety Information

Chemical Safety Summary:
INCHEM
Oxymesterone: http://www.inchem.org/documents/pims/pharm/pim914.htm
Main risks and target organs:
There is no serious risk from acute poisoning, but chronic use can cause harm. The main risks are those of excessive androgens: menstrual irregularities and virilization in women and impotence, premature cardiovascular disease and prostatic hypertrophy in men. Both men and women can suffer liver damage with oral anabolic steroids containing a substituted 17-alpha-carbon. Psychiatric changes can occur during use or after cessation of these agents.
Summary of clinical effects:
Acute overdosage can produce nausea and gastrointestinal upset. Chronic usage is thought to cause an increase in muscle bulk, and can cause an exageration of male characteristics and effects related to male hormones. Anabolic steroids can influence sexual function. They can also cause cardiovascular and hepatic damage. Acne and male-pattern baldness occur in both sexes; irregular menses, atrophy of the breasts, and clitoromegaly in women; and testicular atrophy and prostatic hypertrophy in men.
Diagnosis:
The diagnosis depends on a history of use of oral or injected anabolic steroids, together with signs of increased muscle bulk, commonly seen in "body-builders". Biochemical tests of liver function are often abnormal in patients who take excessive doses of oral anabolic steroids. Laboratory analyses of urinary anabolic steroids and their metabolites can be helpful in detecting covert use of these drugs.
First aid measures and management principles:
Supportive care is the only treatment necessary or appropriate for acute intoxication. Chronic (ab)users can be very reluctant to cease abuse, and may require professional help as with other drug misuse.

Oxymesterone Safety Data Sheet (PDF 6 pages):
https://www.trc-canada.com/prod-img/MSDS/O876425MSDS.pdf